This module describes the role and nature of accelerated partial breast irradiation (APBI) in breast cancer treatment plans, particularly after breast-conserving surgery and in contrast to conventional whole breast irradiation (WBI). Thorough discussion of the advantages and disadvantages of these techniques is followed by description of APBI patient selection criteria; use of the MammoSite^® device for APBI; patient education; and potential adverse events. An overview of current clinical literature on the use of APBI concludes the module. Approved for Category A credits. Course expiration February 1, 2010.

This activity may be available in multiple formats or from different sponsors. The ARRT does not allow CE activities such as internet courses, home study programs or directed readings to be repeated for CE credit in the same or any subsequent biennium.

1. List current techniques for whole breast irradiation after breast-conserving surgery including teletherapy, LDR, and HDR.
2. State the irradiation technique that is currently "standard of care" following breast-conserving surgery.
3. Give advantages and disadvantages of WBI using HDR, LDR, or teletherapy.
4. Discuss mastectomy versus breast-conserving surgery.
5. Define Whole Breast Irradiation (WBI) and Accelerated Partial Breast Irradiation (APBI) and explain basic techniques.
6. Give advantages and disadvantages of WBI and APBI.
7. Explain the rationale for APBI.
8. Explain brachytherapy techniques for APBI.
9. List important criteria for the selection of patients for MammoSite^®APBI.
10. Describe the MammoSite^®technique for PBI.
11. List the criteria used for evaluation of the MammoSite^®implant for appropriateness of treatment.
12. List important points in patient education for MammoSite^®patients.
13. List the most likely adverse events associated with MammoSite^® treatments.
14. Discuss the current clinical experience with APBI.

Arthur DW, Vicini FA, et al. Accelerated partial breast irradiation: an updated report from the American Brachytherapy Society. Brachytherapy, 2002;1:184–190.

Dowlatshahi K, Snider HC, et al. Early Experience with Balloon Brachytherapy for Breast Cancer. Arch Surg, 2004;139:603-608.

Kuerer HM (Moderator). Anderson Cancer Center Telemedicine Symposium. The Case for Accelerated Partial-Breast Irradiation for Breast Cancer. Contemporay Surgery, 2003; 58:508-517.

Vicini FA, Baglan KL, et al. Accelerated Treatment of Breast Cancer. Journal of Clinical Oncology, 2001;19:1993-2001.

Vicini FA, Kestin L, et al. Limited-Field Radiation Thearpy in the Management of Early-Stage Breast Cancer. Journal of the National Cancer Institute, 2003;95:1205-1211.