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Title

Radiation Biology, Part 4: Genetic Effects of Radiation (1 credit hours)

Abstract

Genetic Effects of Radiation is the fourth of eight in the Radiobiology and Radiation Protection program. This module will introduce you to how radiation can cause genetic damage and how that damage may be passed on to future generations. The topics discussed build upon the previous modules; it is recommended that those modules be completed before attempting this one. The information provided in this module will help you understand why anyone involved in radiologic science should take a conservative approach when assessing the potential risks of exposure.

Course Approval Expiration/End Date: August 1, 2011 Category A Credit

Author

Elsevier Inc.,

This module is adapted from Mosby's Radiography Online: Radiologic Physics, copyright © 2002 - 2004 by Elsevier (USA) reproduced by permission of Elsevier Inc. and edited for use as CE content by Denise Moore, Professor of Radiology, Sinclair Community College.

Objectives

Upon completion of this module, the learner should be able to:

Define the important terms in the module.
Describe how radiation can cause minor changes in DNA and result in major genetic damage.
Identify the process by which genetic effects of ionizing radiation can be passed to future generations.
Compare and contrast dominant, recessive, and sex-linked gene mutations.
Describe why it is prudent to take a conservative approach to radiation risk assessment.
Identify how ionizing radiation causes chromosomal aberrations.
Describe how scientists estimate the risk of radiation-induced genetic mutations and explain why accurate risk estimates are difficult to make.
Describe why radiography is a safe occupation when appropriate radiation protection is taken.
Identify why one of the best defenses against genetic mutation is protection of the gonadal region from ionizing radiation.

Resources

Neel JV, Schull WJ, Eds. The Children of Atomic Bomb Survivors: A Genetic Study. Washington, DC: National Academy Press; 1991.

Neel JV. The Genetic Effects of Ionizing Radiation on Humans. 1998-2002. Available at: http://ibis-birthdefects.org/start/neelppr.htm. Accessed July 1, 2009.

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